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KMID : 0383820120730010032
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Tuberculosis and Respiratory Diseases
2012 Volume.73 No. 1 p.32 ~ p.37
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Bacterial Pathogens of Ventilator Associated Pneumonia in a Tertiary Referral Hospital
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Chi Su-Young
Kim Tae-Ok
Park Chan-Woo
Yu Jin-Yeong
Lee Bo-Ram
Lee Ho-Sung
Kim Yu-Il
Lim Sung-Chul
Kwon Yong-Soo
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Abstract
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Background: This study evaluates the bacterial pathogens of Ventilator-associated pneumonia (VAP) in a tertiary referral hospital.
Materials and Methods: A total of 109 bacterial pathogens from 91 adult patients with VAP, who were admitted to the medical intensive care unit from January 2008 to December 2009, were examined. Clinical characteristics, bacterial pathogens, and resistance profiles were analyzed.
Results: Staphylococcus aureus (44%) was the most frequently isolated. Acinetobacter baumanii (30%), Pseudomonas aeruginosa (12%), Stenotrophomonas maltophilia (7%), Klebsiella pneumoniae (6%), and Serratia marcescens (2%) were isolated from the transtracheal aspirates or bronchoalveolar lavage in patients with VAP. There was no significant difference of bacterial pathogens between early and late onset VAP. All isolated S. aureus were methicillin resistant S. aureus; the imipenem resistance rate of A. baumanii was 69%.
Conclusion: The two most frequent pathogens of VAP were S. aureus and A. baumanii. There were no pathogenic differences between early and late onset VAP.
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KEYWORD
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Pneumonia, Ventilator Associated, Staphylococcus aureus , Acinetobacter baumanii
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